Karimi Zandi, Nahid (2016) Evaluation effects of using genomic information on breeding value estimation of some trait in the mice stocks. Masters thesis, university of zabol.
|
Text
Evaluation effects of using genomic information on breeding value.pdf Download (193kB) | Preview |
Abstract
The identification of animals with high genomic potential, is a first step in design breeding strategy, is currently mainly rely on the animals phenotypic and pedigree information’s. However, the advent of advanced molecular markers proposed as tool to aid to overcome limitations of the classical selection methods. Obesity, mainly defined by body mass index, is an important economic trait, however, its underlying genetic regulatory mechanisms is largely unknown. Therefore, in the present study, we aimed to first assess the benefits of using genomic information on the accuracy of estimated breeding value for BMI trait and second to determine the contribution of dominance variance in explanation of proportion of BMI variability. In order to achieve these goals, we have analyzed genomic and phenotypic data of 440 crossbreed mice using two different model schemes, with and/or without genomic data. The results of the present study demonstrate that using combining phenotypic and genotypic are helpful in improvement of the accuracy of breeding value estimation. Besides, using statistical models based on combining phenotypic and genotypic data, we found that only about 1.7% of the BMI variance were explained by dominance genetic variance. Finally the result of this research; first provide the evidence for validating the practical value of using genomic on the increasing the accuracy of estimated breeding value of BMI trait; at the second, only very small proportion of BMI variance may explained by dominance genetic variance in analyzed population.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | breeding value, molecular marker, heterogenic mouse, body mass index |
| Subjects: | Q Science > QH Natural history |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 10 Nov 2019 07:08 |
| Last Modified: | 10 Nov 2019 07:08 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/2567 |
Actions (login required)
 |
View Item |
