Synthesis of new pyrazole derivatives in glycerol-potassium carbonate as eutectic solvent and study of their antibacterial effects

Motraqi, Z. (2017) Synthesis of new pyrazole derivatives in glycerol-potassium carbonate as eutectic solvent and study of their antibacterial effects. Masters thesis, university of zabol.

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Abstract

One of the most useful ring systems, which are heterocyclic chemical compounds that make up the bases of many of these compounds , Pyrazole derivatives due to their numerous applications in agriculture, pharmaceuticals and dyes are of particular importance . In this study, new derivatives of 5-amino-1- (2,4-di nitrophenyl) -1 H- pyrazole-4-carbonitril-3-substituted by a one-pot reaction of potassium carbonate was synthesized multi-component solvent glycerol autectic The distinguishing feature of this method can be used to carry out the reaction at relatively low temperatures, high efficiency and environmentally-friendly process being noted. Finally synthesized derivatives inhibitory effect on the number of gram positive and negative bacteria and three fungi were investigated.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Eutectic Solvents, Green Chemist, Pyrazole Derivatives, Antibacterial Effects, Antifungal effects
Subjects: Q Science > QD Chemistry
Depositing User: Mrs najmeh khajeh
Date Deposited: 19 May 2018 06:02
Last Modified: 04 Mar 2019 07:00
URI: http://eprints.uoz.ac.ir/id/eprint/1778

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