Mohamadzade Shahroudi, Z. (2016) Prevalence of Genes Encoding Microcins in Escherichia coli Isolates Collected from Patients with Urinary Tract Infection in Sistan. Masters thesis, university of zabol.
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Abstract
Uropathogenic Escherichia coli is the main pathogen in urinary tract infections. Microcins was produced in urine as the one of the most important products that be synthesized by UPEC extracelluarly, which helps to develop urinary tract infection. The first step to confront and inhibit of this pathogen is the identification of the major virulence factors. The main objective of this study was to determine the frequency of genes encoding Microcins (mcm, mch, mcb, mcl, mcv, mcj and mcc) determined. The study were conducted on 100 Escherichia coli isolates.These genes frequency were performed Multiplex-PCR and Uniplex-PCR method. A total of the 100 Escherichia coli isolates, mcm gene with 34% highest frequencies and mcb, mcl and mcc genes were not detected in any of the isolates the lowest frequencie, respectively. Gene frequency for mcv, mch and mcj genes were detected 27%, 22% and 1% respectively. The results showed that mcm, mch, mcv most common disease-causing genes in E. coli isolated from urinary tract infection is in the city of Zabol. This could be information about the importance of infection in genitourinary pathology, management - CVI and provide treatment strategies.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Microcin, Urinary Tract Infection, Uropathogenic Escherichia coli (UPEC) |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Depositing User: | admin admin1 admin2 |
| Date Deposited: | 23 May 2017 05:10 |
| Last Modified: | 23 May 2017 05:10 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/1357 |
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