Najafi, M. (2017) Homogeneous liquid-liquid microextraction of methadone and tramadol using a switchablehydrophilicity solvent and determination by gas chromatography. Masters thesis, university of zabol.
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Abstract
In this work, a new method base on homogeneous liquid–phase microextraction was developed for the determination of methadone and tramadol in biological samples. Dipropylamine was used as extraction solvent with switchable hydrophilicity that can be miscible/immiscible upon the addition or removal of CO2 as a reagent. The effects of operational parameters of the extraction such as volume of acceptor phase, volume of donor phase, pH of donor phase, and ionic strength of solution were investigated. Under optimal conditions, the preconcentration factors, the detection limits and the linearity of the method were achieved in the ranges of 135-138, 1.2 μgL−1 and 4–1000 μgL−1 respectively. Finally, the proposed method has been successfully applied to the analysis of methadone and tramadol in biological samples
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Homogeneous liquid-liquid microextraction, Switchable hydrophilicity solvent, Mono and dinitro toluenes, Gas chromatography |
| Subjects: | Q Science > QD Chemistry |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 12 Sep 2018 09:04 |
| Last Modified: | 06 Mar 2019 07:03 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/2154 |
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