Synthesis and evaluation of antibacterial activity of new pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives

Beyzaei, Hamid (2017) Synthesis and evaluation of antibacterial activity of new pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives. Technical Report. University of zabol.

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Abstract

In this study, a new and efficient two step procedure was proposed for the synthesis of some novel pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-d] pyrimidine derivatives. The chemical structure of all compounds was deduced from 1H NMR, 13C NMR, FT-IR and elemental analyses. The in vitro antibacterial activities of the newly synthesized derivatives were evaluated against a wide range of Gram-positive and -negative bacterial strains of various genera, which then compared with current antibiotics and reported as inhibition zone diameter (IZD), minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. The derivatives showed moderate to good inhibitory activities against pathogenic bacteria.

Item Type: Monograph (Technical Report)
Subjects: Q Science > QD Chemistry
Depositing User: admin admin1 admin2
Date Deposited: 14 Jun 2017 06:06
Last Modified: 14 Jun 2017 06:06
URI: http://eprints.uoz.ac.ir/id/eprint/1542

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