P42 tumor suppressor gene expression evaluation in esophagus cancer patients

Keshtegar, M. (2015) P42 tumor suppressor gene expression evaluation in esophagus cancer patients. Masters thesis, University of Zabol.

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Abstract

Esophagus cancer has the sixth rank in terms of incidence and the ninth rank in terms of mortality among cancers. About 100 thousand people have suffered from Esophagus cancer around the world last year. Almost %10 of the cancers are treated by basic surgical treatment but identifying cases with high probability of recursion is a major problem in clinical management of disease. At the present, the stage of lymph node is the most exact prediction of disease recursion. In Iran, unlike the other countries, the women suffer from the cancer more and unfortunately, the interior statistics represent that patients in the country of medical treatments have one of the lowest cancers and their 1-year survival is less than 40 percent. The presence of p61INK4a was considered for the first time when testing changes in compounds of cyclone-CDK complexes in transformed cells by the virus SV20. The research aims to evaluate the p42 gene expression in patients suffering from Esophagus cancer to achieve medical purposes. The present research was performed using the technique Real-time PCR and the statistical software spssv05. Statistical findings didn’t show significant increase in expressing p42 gene in cancerous tissues of Esophagus than witness samples.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Esophagus cancer, p42 gene, Real-time PCR, gene expression
Subjects: Q Science > QH Natural history > QH301 Biology
Depositing User: admin admin1 admin2
Date Deposited: 01 Nov 2016 07:17
Last Modified: 01 Nov 2016 07:17
URI: http://eprints.uoz.ac.ir/id/eprint/950

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