Design and synthesis of two nanocatalysts supported MCM-41 and their application as a novel green method in pyrimidine synthesis using various chalcone derivatives as starting materials

dianati pur, Tahere (2014) Design and synthesis of two nanocatalysts supported MCM-41 and their application as a novel green method in pyrimidine synthesis using various chalcone derivatives as starting materials. Masters thesis, University of Zabol.

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Abstract

Pyrimidine derivatives have taken part in many beneficial medicinal agents and great numbers of biological, therapeutic and medicinal effects have been reported about them. So, many signiicant studies have been done toward finding novel and more efficient syntheticmethodologies for their synthesis. In the present study, starting from chalcone derivatives, we tried to report a novel echofriendly protocol for the facile synthesis of some new trisubstituted pyrimidines. Two nanocatalysts, based on MCM-41 porous material have been designed and used to catalyze the reaction of chalcones with amidine derivatives in order to prepare pyrimidine derivatives.The optimized reaction conditions were studied to reach to the best results of yields and reaction times. Various advantages could be reported for the present methodology such as relatively short reaction times, simple work-up, and good to excellent yields of the products.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Nanocatalysts, Chalcone derivatives, Trisubstituted pyrimidine derivatives, Green chemistry
Subjects: Q Science > QD Chemistry
Depositing User: admin admin1 admin2
Date Deposited: 24 Apr 2016 04:07
Last Modified: 24 Apr 2016 04:07
URI: http://eprints.uoz.ac.ir/id/eprint/471

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