Zahedi nasab, R. (2022) Prevalence of three NDM-1, oqxA and oqxB genes in Klebsilla pneumoniae isolates isolated from urine samples. Masters thesis, university of zabol.
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revalence of three NDM-1, oqxA and oqxB genes in Klebsilla pneumoniae isolates isolated from urine samples.pdf Download (145kB) | Preview |
Abstract
The most important factors causing antibiotic resistance in Klebsiella pneumoniae bacteria are beta-lactamases and secretory pumps, considering the high prevalence of genes causing resistance and the spread of hospital infections, especially urinary tract infections caused by them, in this Research Klebsiella pneumoniae isolates isolated from urine samples were checked for the abundance of NDM-1, oqxA and oqxB genes using PCR technique. Boiling method was used to extract DNA. Out of the 95 investigated isolates, the prevalence of oqxA, oqxB and NDM-1 genes was evaluated in 75 isolates (78.94%), 75 isolates (78.94%) and 84 isolates (88.42%), respectively. The spread of antibiotic resistance genes in this study is a cause for concern, therefore, to control infection and prevent the spread of drug-resistant bacteria, there is a need to manage antibiotic administration and use molecular methods such as PCR to identify resistant isolates.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Klebsiella pneumoniae, antibiotic resistance, urinary tract infection, NDM-1, oqxA, oqxB |
| Subjects: | Q Science > QH Natural history > QH426 Genetics |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 28 Sep 2024 16:34 |
| Last Modified: | 28 Sep 2024 16:34 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/3633 |
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