The prevalence of aminoglycoside modifying enzyme coding genes among Pseudomonas aeruginosa strains isolated from patients hospitalized in Sistan region hospitals

purgolestani, mahdi (2023) The prevalence of aminoglycoside modifying enzyme coding genes among Pseudomonas aeruginosa strains isolated from patients hospitalized in Sistan region hospitals. Masters thesis, university of zabol.

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Abstract

Pseudomonas aeruginosa is one of the most important causes of widespread infections in patients hospitalized in different hospital departments. One of the most important problems related to the treatment of Pseudomonas infections is resistance to aminoglycoside antibiotics.This research was conducted with the aim of investigating the abundance of genes encoding aminoglycoside modifying enzymes in Pseudomonas aerogenosa isolated from patients hospitalized in Zabul city hospital. From the DNA of 60 isolates of Pseudomonas aerogenosa isolated from patients hospitalized in Zabul Hospital, only 55 isolated were positive (91.66%) and 5 isolated (8.33%) were negative. The investigated related to aadb gene with 29 isolated (48.33%) and the lowest amount of genes related to aac and aadA gene with 10 isolated (10%). The result of this research showed that the presence of aadb gene with the amount of 29 isolates out of 55 positive isolates in Pseudomonas aeruginosa can increase the biological resistance and the possibility of resistant strains among Gram-negative bacteria

Item Type: Thesis (Masters)
Uncontrolled Keywords: Pseudomonas aeruginosa, aminoglycoside, Zabul, aadb gene, aadA gene
Subjects: Q Science > QH Natural history > QH426 Genetics
Depositing User: Mrs najmeh khajeh
Date Deposited: 28 Apr 2024 05:41
Last Modified: 28 Apr 2024 05:41
URI: http://eprints.uoz.ac.ir/id/eprint/3595

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