Farifteh, Fatemeh (2023) Development of a new method based on combination of gel-electromembrane extraction with switchable hydrophilicity solvent-based liquid-liquid microextraction for the determination of atropine. Masters thesis, university of zabol.
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Development of a new method based on combination of gel-electromembrane extraction with switchable hydrophilicity solvent-based liquid-liquid microextraction for the determination of atropine.pdf Download (212kB) | Preview |
Abstract
In this study, a new method based on a combination of electromembrane gel with liquid-liquid microextraction based on a switchable hydrophilicity solvent and its detection by gas chromatography-mass spectroscopy for preconcentration of atropine and its detection in real samples including human urine, tap water, and drinking water is developed. Experimental parameters have been optimized for both electromembrane extraction and SHS solvent-based liquid-liquid microextraction. Using agarose gel membrane, analytes were extracted from 10 mL of sample solution to 500 μL of acceptor phase. The maximum value is determined in the optimal conditions of pH of the acceptor solution 10, pH of the sample solution 5, voltage value of 30 volts and extraction time of 25 minutes. Then the acceptor solution was transferred to the test tube and the experimental conditions of the second stage were optimized. Optimum conditions, linear range in the range of 5-500 micrograms/liter, detection limit 1.5 micrograms/liter and preconcentration factor 170.6 were obtained. Finally, the proposed method makes it possible to determine the target analyte in urine samples, tap water and drinking water with acceptable accuracy.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Gel-electromembrane extraction, liquid-liquid microextraction based on switchable hydrophilicity solvent, homogeneous liquid-liquid microextraction, atropine, gas chromatography-mass spectrometry |
| Subjects: | Q Science > QD Chemistry |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 15 Jan 2024 05:49 |
| Last Modified: | 15 Jan 2024 05:49 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/3496 |
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