The Protective Effects of Prosopis farcta Seed Extract on Thioacetamide-Induced Acute Renal toxicity and Histopathology in Rat

Pourkarami, Najmeh (2019) The Protective Effects of Prosopis farcta Seed Extract on Thioacetamide-Induced Acute Renal toxicity and Histopathology in Rat. Doctoral thesis, University of Zabol.

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Abstract

Herbs have a wide range of Antioxidant, kidney is a metabolic organ in the body, which plays a role in trapping and refining poison. The combination of antioxidants with herbal sources has useful effect on liver function. In this survey, the protective effect of Prosopis Farcta seed Hydro-alcoholic extract against a cute Hepatotoxicity resulted from Thioacetamide in rat was studied. In this study, 40 male rats were divided to 4 groups with 10 members in each group. The first group, received the physiology serum orally. The second group, received the Thioacetamid injection with 50 mg/kg dosage at an interval of 24 hours in IP form and after passing 3 days of last injection, they received the physiology serum in IP form. Like the second group, the third group was poisoned and received hydro-alcoholic extract, after extraction and purification with 200 mg/kg for 3 weeks. Serum BUN and serum creatinine were measured after blood sampling and serum separation. In addition, after the aeration with ether, a portion of the kidney was also sampled to observe tissue changes.

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: kidney, Prosopis farcta, thioacetamide, rat
Subjects: R Medicine > RB Pathology
Depositing User: Mrs najmeh khajeh
Date Deposited: 06 May 2019 08:27
Last Modified: 06 May 2019 08:27
URI: http://eprints.uoz.ac.ir/id/eprint/2442

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