Mohammadi-Asl, Halimeh (2017) Novel green synthesis of tetrazole derivatives using nitriles and aldehydes as starting materials. Masters thesis, university of zabol.
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Novel green synthesis of tetrazole derivatives using nitriles and.pdf Download (184kB) | Preview |
Abstract
In this research project, natural clinoptilolite pores were modified by ZnO and Bi2O3 nanoparticles and the application of the as-prepared nanocomposite catalysts in the synthesis of 5- aryl-1H-tetrazoles was studied. The morphology and chemical structure of the as-prepared catalyst was characterized by XRD, SEM, TEM, FTIR and EDX analyses. The catalysts were applied in the direct synthesis of 5-aryl-1H-tetrazoles through [3+2] cycloaddition reaction of benzonitrile derivatives with sodium azide and the three component ZnO/Bi2O3/Zeolite nanocomposite was found as the best and optimum catalyst. The optimum reaction conditions including solvent, temperature and catalyst loading were studied. The tetrazole derivatives were then synthesized through using various nitriles as starting materials. Then, the synthesis of terazoles from benzaldehydes as the starting material through a three-component reaction was also examined under optimum reaction conditions in the presence of optimum catalyst. All of the products were obtained with high purity and good to excellent yields. Appropriate reaction times, simple workup and catalyst reusability were among the advantages of the present protocol
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Novel green synthesis, tetrazole derivatives, nitriles, aldehydes, starting materials |
| Subjects: | Q Science > QD Chemistry |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 20 May 2018 05:48 |
| Last Modified: | 04 Mar 2019 05:47 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/2091 |
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