Heidari, Hossein (2017) Multi-component synthesis of 2-(alkylsulfuylphenylamio- methylene)malononitrile derivatives and evaluation of their antibacterial and antifungal effects. Masters thesis, university of zabol.
|
Text
Multi-component synthesis of 2-(alkylsulfuylphenylamio.pdf Download (177kB) | Preview |
Abstract
2-(Alkylsulfonyl-phenylamino-methylene)malononitrile is used as the intermediate or final product in the synthesis of heterocyclic compounds such as 1,4-thiazepines, thiazoles and thiophenes. Antimicrobial properties of 1,4-thiazepines, thiazoles and thiophanes have been studied. In addition, several reportes have been published on pharmaceutical and biochemical applications of these derivatives. But, the antimicrobial properties of 2-(alkylsulfonylphenylamino- methylene)malononitrile derivatives have not been considered. In this research, some new 2-(alkylsulfonyl-phenyl amino-methylene)malononitrile derivatives were synthesized via a novel and green method. Short reaction time, high efficiency and environmentally friendly process are significant features of applied method. Finally, the antimicrobial properties of the compounds were evaluated on several bacterial and fungal pathogenes. The effects of substituent changes on their inhibitory activity were also investigated.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | 2-(Alkylsulfonyl-phenylamino-methylene)malononitrile, Isothiocyanate,Malononitrile, Benzyl halide, Solvent-free conditions |
| Subjects: | Q Science > QD Chemistry |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 19 May 2018 04:32 |
| Last Modified: | 04 Mar 2019 07:02 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/1714 |
Actions (login required)
 |
View Item |
