Shirazinia, Reza (2017) Effect of the hydroalcholic extract of Opuntia dillenii and Averrhoa carambola on the oxidative stress following liver injury using Lead acetate in male wistar rats. Doctoral thesis, university of zabol.
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Abstract
This research was conducted to evaluate the anti-inflammatory and the healing effects of hydroalcholic extract of averroa carambola and opuntia dillenii on lead induced hepatic injury.In this research we used 36 male wistar rats randomly divided into 6 group (n=6) including control group: negative control Lead group: the group intoxicated by intra peritoneal injection of lead acetate K100 group: the group intoxicated by intra peritoneal injection of lead acetate and treated by 100mg/kg of hydroalcholic extract of opuntia dillenii K200 group: the group intoxicated by intra peritoneal injection of lead acetate and treated by 200mg/kg of hydroalcholic extract of opuntia dillenii S100 group: the group intoxicated by intra peritoneal injection of lead acetate and treated by 100mg/kg of hydroalcholic extract of Averrhoa carambola S200 group: : the group intoxicated by intra peritoneal injection of lead acetate and treated by 200mg/kg of hydroalcholic extract of Averrhoa carambola The research was prolonged for 10 days and the approach was including the protection of rats by oral gavage of Averrhoa carambola and opuntia dillenii and the intoxication of them in addition to oral gavage of the extract in the other 5 days of period. The antioxidant situation of the serum was evaluated by MDA assessment in the TBARS approach and liver injury was evaluated by AST,ALT,ALP assessment . The statical analysis of TBARS of the samples showed a significant reduction in both hydroalcholic extract treated groups including 100mg/kg and 200mg/kg treated groups (P<0.001 for all cases).
| Item Type: | Thesis (Doctoral) |
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| Uncontrolled Keywords: | Opuntia dillenii,Averrhoa carambola ,oxidative stress,lead acetate,liver |
| Subjects: | S Agriculture > SF Animal culture |
| Depositing User: | Mrs najmeh khajeh |
| Date Deposited: | 16 May 2018 07:22 |
| Last Modified: | 05 Mar 2019 06:26 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/1697 |
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