Study of thiazole synthesis using various hydrazines and hydrazides derivatives

moghadas, Hadi (2015) Study of thiazole synthesis using various hydrazines and hydrazides derivatives. Masters thesis, university of zabol.

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Abstract

A facile one-pot two-step process for the synthesis of ethyl 2-imino-4-methyl-2, 3- Dihydrothiazole-5-carboxylates via the cyclocondensation of ethyl 2- hiocyanatoacetoacetate with a variety of hydrazine and hydrazidederivatives has been developed.Ethyl 2-thiocyanatoacetoacetate itself has been synthesized as intermediate from the reaction of ethyl 2-chloroacetoacetate with potassium thiocyanate (KSCN).The molecular structures of these newly synthesized compounds were elucidated on the basis of elemental analysis and spectral data.

Item Type: Thesis (Masters)
Uncontrolled Keywords: three-component reaction;thiocyanation;thiazole derivatives; cyclocondensation;hydrazines;hydrazides.
Subjects: Q Science > QD Chemistry
Depositing User: admin admin1 admin2
Date Deposited: 30 May 2017 08:07
Last Modified: 30 May 2017 08:07
URI: http://eprints.uoz.ac.ir/id/eprint/1412

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