Investigation of histopathological effects of L-Carnitine and nitric oxide on kidneyof male diabetic rats

Panahi, N. (2016) Investigation of histopathological effects of L-Carnitine and nitric oxide on kidneyof male diabetic rats. Masters thesis, university of zabol.

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Abstract

kidney is a Metabolic organ that is confronting with chemical things and drugs.In this article we discuss about the way of intercurrenting L-Carnitin and LArginine in index of kidney injury in field mouse. In our experiments we divided 50 field mouse in 5 group and stricked them to diabetes by injecting 120 mg of Alloxan.we fed them in 30 days.at the end of the experiment we measured blood glucose and other biochemical parameters and then for realizing Histopathologicchanges we fainted them and killed them and checked the sample of kidney by two method: 1.Hematoxylin-Eosin 2.guard using optical microscope. Final result represents that using L-Arginine and LCarnitin has a positive effection in controlling diabetes.using both L-Carnitin and L-Arginine synchronicly has a synergist effection and most positive effect in controlling diabetes. In pathologic experiments in the first group kidney tissue and tubule's situation was normal and there was no toll pathologic. In second group blood glucose increased and we saw swellen cells and Glomerulosclerosis. In third group L-Carnitin has more remedial effection than second group and finaly treatment with both L-Carnitin and L-Arginine has the most improvement.

Item Type: Thesis (Masters)
Uncontrolled Keywords: L-Carnitin, L-Arginine,Field mouse,Diabetes, Histopathologic
Subjects: S Agriculture > SF Animal culture
Depositing User: admin admin1 admin2
Date Deposited: 21 May 2017 05:31
Last Modified: 21 May 2017 05:31
URI: http://eprints.uoz.ac.ir/id/eprint/1341

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