Shokuhi nia, M. (2014) Prevalence of Virulence Genes in Uropathogenic Escherichia coli Strains Isolated from Patients with Urinary Tract Infection in Sistan. Masters thesis, University of Zabol.
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Prevalence of Virulence Genes in Uropathogenic Escherichia coli Strains Uropathogenic Escherichia coli Strains.pdf Download (242kB) | Preview |
Abstract
Uropathogenic Escherichia coli is the main pathogen in urinary tract infections. These strains carry major virulence factors such as; invasins, siderophores and toxins, which helps to develop urinary tract infection. The first step to confront and inhibit of this pathogen is the identification of the major virulence factors. Phylogenetic studies have revealed that gene encoding Toxins an important role in the pathogenesis. The main objective of this study was to determine the frequency of virulence factors genes encoding, toxins (cvi/cva, iss, vat, astA and cdtB), Iron acquisition systems (iutA), Capsule Lipopoly Saccharides (neuS and kpsII) and Invasins(ibeA and tsh) determined using Multiplex PCR method. A total of the 100 Escherichia coli isolates, iutA gene with 99% highest frequencies and cdtB gene was not detected in any of the isolates the lowest frequencies, respectively. Gene frequency for kpsII, neuS, ibeA, iss, astA, cvi/cva,vat and tsh genes were detected 98%, 96%, 67%, 47%, 29%, 19%, 18% and 1% respectively.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Invasin, Siderophore, Toxin, Virulence genes, Uropathogenic Escherichia coli (UPEC) |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Depositing User: | admin admin1 admin2 |
| Date Deposited: | 04 Dec 2016 06:53 |
| Last Modified: | 04 Dec 2016 06:53 |
| URI: | http://eprints.uoz.ac.ir/id/eprint/1070 |
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