Clinical evaluation of epidural injection of MgSO4 and Xylazine in dog

Rezaei, Saeed (2016) Clinical evaluation of epidural injection of MgSO4 and Xylazine in dog. Doctoral thesis, University of Zabol.

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Objective- The aim of this study was to evaluate clinically localized or systemic effects of epidural injections of MgSO4 alone and in combination with xylazine in dogs. Design- Experimental study Animals- Six healthy mixed breed dogs. Procedures- The experiments were performed crossover method. After administration of the 1 ml lidocaine 2% under the skin of lumbosacral region for local anesthesia, 10 mg/kg of Mgso4 20%, 0.3 mg/kg of Xylazine 2% and combination of Mgso4-xylazine were administration with doses mentioned in three groups. The Respiratory rate, heart rate, rectal temperature, reaction to pain, sedation and motor block were recorded prior and after (5, 10, 15, 20, 30, 40, 50, 60, 90 and 120 minutes) epidural injection. Results- There were No statistically significant difference in mean respiratory rate, heart rate and rectal temperature (p-value>0.05); but showed significant differences in heart rate at 30 and 40 Minutes in groups (p-value<0.05). Significant differences in response to pain in minutes 10, 15, 20, 30, 40, 50, 60 and 90 minutes, for sedation at 15, 20, 30, 40 and 50, to motor block in minutes 10, 15, 20, 30, 40 and 50, there was after epidural administration between different groups; There was no significant difference in other times. Conclusion and clinical relevance- Epidural administration the combination of MgSO4-xylazine is appropriate for pain management in surgery of the lower limbs to provide enough time to do Surgery that need more time.

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: MgSO4, Xylazine, Epidural, Dog
Subjects: S Agriculture > SF Animal culture
Depositing User: admin admin1 admin2
Date Deposited: 29 Nov 2016 07:04
Last Modified: 29 Nov 2016 07:04

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